Ready to go?

The Giants travel to Baltimore for their annual must-win Week 16 game. Drew Brees looks to spoil the Cowboys’ division-title dreams. And the reeling Bears will try to avoid the same fate the Lions endured last week in the Arizona desert. Adrian Peterson, Aldon Smith and Calvin Johnson all have long-standing records in their sights. The Rams continue to eye a winning record. The Broncos and Patriots aim to win and stay healthy against overmatched opponents.

No Thursday night football, no Monday night football — but plenty of fun over the weekend. Here are the Week 16 storylines.

— Peter Schrager